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VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor with
VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor with
VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor with
VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor with

VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor with

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VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor withVTP 27999 is a highly potent and selective renin inhibitor (IC50 = 0. 47 nM). VTP 27999 demonstrated excellent selectivity over related and unrelated off targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension, and good exposure in humans. Product information CAS Number: 1013937 63 7 Molecular Weight: 639. 10 Formula: C28H42ClF3N4O7 Synonym: VTP 27999, 2, 2, 2 trifluoroacetate VTP27999, 2, 2,

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Description

and efficacious SHP2 inhibitor with IC50 =0

57(10):4213-38

Smiles: CC#C[C@@H](CC(O)=O)C1C=CC(=CC=1)OCC1=CC(=CC=C1)C1C=CC(=CC=1)C(F)(F)F

InChiKey: KFSKTWYDIHJITF-UHFFFAOYSA-N

Molecular Weight: 1295

VTP-27999 TFA - a renin inhibitor. CAS# 1013937-63-7 Size:Solid 2 mg and efficacious SHP2 inhibitor withVTP 27999 is a highly potent and selective renin inhibitor (IC50 = 0. 47 nM). VTP 27999 demonstrated excellent selectivity over related and unrelated off targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension, and good exposure in humans. Product information CAS Number: 1013937 63 7 Molecular Weight: 639. 10 Formula: C28H42ClF3N4O7 Synonym: VTP 27999, 2, 2, 2 trifluoroacetate VTP27999, 2, 2,

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