Nitisinone 7439 InChi: InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11

InChi: InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11

both of which are essential for the G1 to S transition

and disrupts c-Met signal transduction pathways

CAS Number: 131359-24-5

with elimination half-lives of 6

Nitisinone 7439 InChi: InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11Nitisinone, also known as NTBC, is an effective herbicide, is the licensed treatment for the human condition, hereditary tyrosinaemia type 1 (HT 1). Its mode of action interrupts tyrosine metabolism through inhibition of 4 hydroxyphenylpyruvate dioxygenase (HPPD). Nitisinone is a remarkable safe drug to use with few side effects reported. Product information CAS Number: 104206 65 7 Molecular Weight: 329. 23 Formula: C14H10F3NO5 Synonym: NTBC Nitisone