SP-100 Polyclonal Antibody, 100ul Plasmid Preparation Allelic variants of this gene

Allelic variants of this gene have been associated with nicotine dependence

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

An important paralog of this gene is GSDMD

The cytoplasmic domain is involved in activating Rac

Several alternatively spliced transcript variants have been found for this gene

SP-100 Polyclonal Antibody, 100ul Plasmid Preparation Allelic variants of this geneSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one