ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates The light chain confers the

The light chain confers the protease-inhibitor function| while the heavy chains are involved in mediating protein-protein interactions with the components of the extracellular matrix

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is a 2694 amino acid protein that belongs to the WD repeat Neurobeachin family

The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter

Mutations in this gene cause Joubert syndrome

ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates The light chain confers theATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This