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CSPG4 Polyclonal Antibody, 50ul Serological Pipets The crystal structure of the

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CSPG4 Polyclonal Antibody, 50ul Serological Pipets The crystal structure of theA human melanoma associated chondroitin sulfate proteoglycan plays a role in stabilizing cell substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

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Description

The crystal structure of the complex formed by this protein and XRCC4 has been resolved

The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes

down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex

Mutations in this gene result in Hartnup disorder

Binding of this protein to CXCR3 results in pleiotropic effects

CSPG4 Polyclonal Antibody, 50ul Serological Pipets The crystal structure of theA human melanoma associated chondroitin sulfate proteoglycan plays a role in stabilizing cell substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

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