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VASP Polyclonal Antibody, 100ul[BT-AP09470] Immuno Plates Altered levels of this protein

SKU: 8440420366

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PLN141.00 PLN188.00

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VASP Polyclonal Antibody, 100ul[BT-AP09470] Immuno Plates Altered levels of this proteinVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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Description

Altered levels of this protein have been reported in cancers of different organs

This protein has been shown to interact with tumor suppressor protein Rb and the expression of CCND1 is regulated positively by Rb

This protein interacts with the cytoplasmic domain of P-selectin| and may function in the intracellular trafficking of P-selectin

IFNGR1 encodes the ligand-binding chain (alpha) of the gamma interferon receptor

So its expression has been considered as useful marker for atrial cardiomyocytes

VASP Polyclonal Antibody, 100ul[BT-AP09470] Immuno Plates Altered levels of this proteinVasodilator stimulated phosphoprotein (VASP) is a member of the Ena VASP protein family. Ena VASP family members contain an EHV1 N terminal domain that binds proteins containing E DFPPPPXD E motifs and targets Ena VASP proteins to focal adhesions. In the mid region of the protein, family members have a proline rich domain that binds SH3 and WW domain containing proteins. Their C terminal EVH2 domain mediates tetramerization and binds both G and F

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