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The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions

The enzymes display overlapping but distinct substrate specificity

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AP-1 Polyclonal Antibody, 20ul[BT-AP00492] ROS/Nitric Oxide Detection Stay ahead of the gameJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.