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MAGI-2 Polyclonal Antibody, 50ul DNA Synthesis suggesting that down-regulation is the

SKU: 73157793501

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MAGI-2 Polyclonal Antibody, 50ul DNA Synthesis suggesting that down-regulation is theThe protein encoded by MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)interacts with atrophin 1. Atrophin 1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase like domain, and multiple PDZ domains. It has structural similarity to the membrane associated guanylate kinase homologue (MAGUK)

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Description

suggesting that down-regulation is the result of methylation of the gene

The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family

Composed of three domains: a modulating N-terminal domain| a DNA-binding domain and a C-terminal steroid-binding domain

ACYP2 (acylphosphatase 2) encodes the muscle-type isoform (MT)

tissue specificity:Expressed in kidney

MAGI-2 Polyclonal Antibody, 50ul DNA Synthesis suggesting that down-regulation is theThe protein encoded by MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)interacts with atrophin 1. Atrophin 1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase like domain, and multiple PDZ domains. It has structural similarity to the membrane associated guanylate kinase homologue (MAGUK)

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