RAD1 Polyclonal Antibody, 20ul[BT-AP13499] Recombinant Protein Expression GPR139 encodes a member of

GPR139 encodes a member of the rhodopsin family of G-protein-coupled receptors

|tissue specificity:Isoform 1 is strongly expressed in the liver

The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP

RAD1 Polyclonal Antibody, 20ul[BT-AP13499] Recombinant Protein Expression GPR139 encodes a member ofThis gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9 1 1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9 1 1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.