TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis PDCD6IP competes with TSG101 for

PDCD6IP competes with TSG101 for the same binding site

and a widespread distribution in the brain

The protein includes an N-terminal SCAN domain| and seven C2H2-type zinc finger motifs

Contains 2 PLD phosphodiesterase domains

Defects in this gene lead to many pathophysiologic problems

TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis PDCD6IP competes with TSG101 forTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.