Phospho-BRCA1 (S1457) Polyclonal Antibody, 20ul Thermal Control SPZ1 may serve as a
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Phospho-BRCA1 (S1457) Polyclonal Antibody, 20ul Thermal Control SPZ1 may serve as aBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal
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