Unc18-1(Phospho Ser313) Polyclonal Antibody, 50ul Metabolic enzymes The encoded protein (B-cell receptor-associated

The encoded protein (B-cell receptor-associated protein 31) is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis

This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus

Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder

This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor| all three genes may be implicated in the 5-q syndrome

The receptor for this protein is RON tyrosine kinase

Unc18-1(Phospho Ser313) Polyclonal Antibody, 50ul Metabolic enzymes The encoded protein (B-cell receptor-associatedThis gene encodes a syntaxin binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy 4. Alternatively spliced transcript variants have been described.