DNJB2 Polyclonal Antibody, 20ul Cytokines Myocardial infarction and acute stroke

Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein

most of them are pseudogenes thought to have arisen from retropositional events

This protein functions as a nucleotide exchange factor for another unfolded protein response protein

also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22% amino acid identity with IL-10

Another variant encoding an N-terminally truncated isoform has been reported

DNJB2 Polyclonal Antibody, 20ul Cytokines Myocardial infarction and acute strokeThis gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.