PTN13 Polyclonal Antibody, 20ul PCR Series such as diabetes and Alzheimer's

such as diabetes and Alzheimer's disease

Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms

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The PDZ-binding motif is essential for stimulated gene transcription

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

PTN13 Polyclonal Antibody, 20ul PCR Series such as diabetes and Alzheimer'sThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma