CUL7 Polyclonal Antibody, 100ul Biomatrix CELSR3 belongs to the flamingo

CELSR3 belongs to the flamingo subfamily

Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome

Weakly expressed in kidney

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Binds directly to the ACTR1A subunit of dynactin

CUL7 Polyclonal Antibody, 100ul Biomatrix CELSR3 belongs to the flamingoThe protein encoded by this gene is a component of an E3 ubiquitin protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.